Neurobiology of Disease MCQs with Answers

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Welcome to the Neurobiology of Disease MCQs with Answers. In this post, we have shared Neurobiology of Disease Online Test for different competitive exams. Find practice Neurobiology of Disease Practice Questions with answers in Biology Tests exams here. Each question offers a chance to enhance your knowledge regarding Neurobiology of Disease.

Neurobiology of Disease Online Quiz

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Test Name: Neurobiology of Disease MCQ Quiz Practice
Type: Quiz Test
Total Questions: 40
Total Marks: 40
Time: 40 minutes

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Neurobiology of Disease

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1 / 40

What is the primary effect of myelin sheath destruction in multiple sclerosis (MS)?

Enhanced synaptic transmission

Increased neurotransmitter release

Disrupted nerve signal transmission

2 / 40

Which disease is characterized by demyelination of neurons in the central nervous system?

Multiple sclerosis

Huntington's disease

Amyotrophic lateral sclerosis

3 / 40

Which neurotransmitter is involved in the reward pathway and addiction?

Dopamine

Glutamate

Serotonin

4 / 40

Which neurotransmitter is implicated in the pathophysiology of depression?

Serotonin

GABA

Dopamine

5 / 40

Which genetic mutation is commonly associated with familial Alzheimer's disease?

Tau protein

Presenilin-1

Synuclein

6 / 40

What is the effect of NMDA receptor overactivation in neurons?

Excitotoxicity

Reduced synaptic transmission

Enhanced neurogenesis

7 / 40

What is the primary role of GABA in the central nervous system?

Neuromodulator

Inhibitory neurotransmitter

Excitatory neurotransmitter

8 / 40

What is the characteristic feature of neurofibrillary tangles in Alzheimer's disease?

Hyperphosphorylated tau protein

Beta-amyloid accumulation

Alpha-synuclein aggregation

9 / 40

What is the primary role of tau protein in neurons?

Enhancing synaptic plasticity

Facilitating neurotransmitter release

Stabilizing microtubules

10 / 40

What is the hallmark symptom of multiple sclerosis?

Muscle weakness and fatigue

Tremors

Memory loss

11 / 40

What is the role of astrocytes in the central nervous system?

Supporting and protecting neurons

Generating action potentials

Modulating neurotransmitter release

12 / 40

What is the role of mitochondria in neurodegenerative diseases?

Synaptic vesicle recycling

Energy production and apoptosis

Neurotransmitter synthesis

13 / 40

What neurotransmitter is deficient in patients with Parkinson's disease?

Acetylcholine

Glutamate

Dopamine

14 / 40

What neurotransmitter is primarily affected in Huntington's disease?

Dopamine

Serotonin

GABA

15 / 40

What is the primary genetic cause of Huntington's disease?

CAG repeat expansion in HTT gene

APP gene mutation

Tau protein mutation

16 / 40

Which disorder is associated with progressive muscle weakness and atrophy?

Parkinson's disease

Amyotrophic lateral sclerosis

Huntington's disease

17 / 40

What is the hallmark feature of Lewy body dementia?

Beta-amyloid plaques

Presence of Lewy bodies

Neurofibrillary tangles

18 / 40

What pathological feature is associated with Creutzfeldt-Jakob disease (CJD)?

Beta-amyloid plaques

Lewy bodies

Prion protein aggregation

19 / 40

Which neurotransmitter is most closely linked to anxiety disorders?

GABA

Acetylcholine

Dopamine

20 / 40

Which area of the brain is primarily affected in Alzheimer's disease?

Hippocampus

Brainstem

Cerebellum

21 / 40

What is the primary cause of Parkinson's disease?

Excessive serotonin levels

Decreased GABA activity

Loss of dopaminergic neurons

22 / 40

What role does glutamate play in excitotoxicity?

Decreased calcium influx

Overactivation of NMDA receptors

Inhibition of synaptic transmission

23 / 40

What is the primary cause of Wernicke-Korsakoff syndrome?

Beta-amyloid accumulation

Thiamine deficiency

Dopamine deficiency

24 / 40

Which neurodegenerative disorder is associated with the ALS-related SOD1 gene mutation?

Multiple sclerosis

Parkinson's disease

Amyotrophic lateral sclerosis

25 / 40

What is the effect of dopamine loss in Parkinson's disease?

Increased anxiety

Motor control impairment

Enhanced memory function

26 / 40

Which brain structure is primarily involved in memory formation?

Basal ganglia

Hippocampus

Cerebellum

27 / 40

Which neurotransmitter is primarily associated with mood regulation?

Serotonin

Acetylcholine

Glutamate

28 / 40

What is the main pathological feature of amyotrophic lateral sclerosis (ALS)?

Myelin sheath destruction

Abnormalities in acetylcholine

Degeneration of motor neurons

29 / 40

Which protein aggregation is associated with Alzheimer's disease?

Beta-amyloid plaques

Alpha-synuclein

Huntingtin protein

30 / 40

Which disorder is characterized by progressive memory loss and cognitive decline?

Alzheimer's disease

Parkinson's disease

Huntington's disease

31 / 40

Which neurodegenerative disease is characterized by chorea and psychiatric symptoms?

Multiple sclerosis

Huntington's disease

Parkinson's disease

32 / 40

Which brain region is commonly associated with the regulation of movement?

Hippocampus

Basal ganglia

Cerebellum

33 / 40

What is the primary function of microglia in the central nervous system?

Synaptic transmission

Neurotransmitter synthesis

Immune response

34 / 40

What is the primary function of neurotrophic factors?

Modulating neurotransmitter release

Supporting neuron growth and survival

Inhibiting synaptic transmission

35 / 40

Which protein is commonly found in the plaques of Alzheimer's disease?

Alpha-synuclein

Beta-amyloid

Prion protein

36 / 40

What is the main function of acetylcholine in the central nervous system?

Inhibiting neuronal firing

Enhancing neurogenesis

Mediating synaptic transmission

37 / 40

What is the primary characteristic of neurodegenerative diseases?

Enhanced neurogenesis

Progressive loss of neuron function

Increased synaptic plasticity

38 / 40

What is the primary role of the substantia nigra in the brain?

Producing dopamine

Processing sensory information

Coordinating voluntary movements

39 / 40

Which gene is commonly mutated in familial forms of amyotrophic lateral sclerosis?

APP

SOD1

HTT

40 / 40

Which protein is implicated in frontotemporal dementia (FTD)?

Alpha-synuclein

Tau protein

TDP-43

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admin3 weeks ago

0 6 1 minute read