Epigenetics and Chromatin Biology MCQs with Answers

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Epigenetics and Chromatin Biology Online Quiz

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Test Name: Epigenetics and Chromatin Biology MCQ Quiz Practice
Type: Quiz Test
Total Questions: 40
Total Marks: 40
Time: 40 minutes

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Epigenetics and Chromatin Biology

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1 / 40

What is the function of the enzyme TET in epigenetics?

Demethylation of DNA

Methylation of DNA

Acetylation of histones

2 / 40

Which protein binds to methylated DNA to mediate gene silencing?

MeCP2

SWI/SNF

TFIID

3 / 40

Which enzyme is involved in the deubiquitination of histones?

Acetyltransferase

Ubiquitin ligase

Deubiquitinase

4 / 40

What is the role of the Polycomb group (PcG) proteins in chromatin biology?

DNA replication

Gene activation

Gene repression

5 / 40

Which protein complex is involved in nucleosome remodeling?

RISC

TFIID

SWI/SNF

6 / 40

What is the role of the Trithorax group (TrxG) proteins in gene regulation?

Gene activation

Gene repression

DNA repair

7 / 40

What is the term for the addition of acetyl groups to histones?

Histone ubiquitination

Histone methylation

Histone acetylation

8 / 40

What is the role of DNA methylation in X-chromosome inactivation?

Activating the X chromosome

Silencing one X chromosome in females

No effect

9 / 40

Which histone mark is associated with heterochromatin formation?

H3K27ac

H3K9me3

H3K4me3

10 / 40

What is the effect of histone methylation on gene expression?

It can activate or repress genes

Always activates genes

Always represses genes

11 / 40

Which protein complex is involved in remodeling chromatin to allow transcription?

SWI/SNF

TFIID

RISC

12 / 40

Which type of RNA is involved in gene silencing through RNA interference (RNAi)?

mRNA

rRNA

siRNA

13 / 40

What is the effect of DNA methylation on gene expression?

No effect

Gene activation

Gene silencing

14 / 40

What is the function of the histone variant H2A.Z?

RNA splicing

Regulating gene expression

DNA replication

15 / 40

Which enzyme removes methyl groups from histones?

Histone demethylase

Histone acetyltransferase

Histone kinase

16 / 40

Which epigenetic mechanism involves the modification of RNA molecules?

RNA editing

RNA splicing

RNA methylation

17 / 40

Which protein complex reads and interprets histone modifications?

DNA polymerases

Histone chaperones

Chromatin reader proteins

18 / 40

What is the effect of histone acetylation on chromatin structure?

Chromatin condensation

Chromatin relaxation

No effect

19 / 40

Which histone modification is commonly associated with gene activation?

Acetylation

Ubiquitination

Methylation

20 / 40

What is the term for the addition of a methyl group to DNA?

DNA methylation

DNA phosphorylation

DNA acetylation

21 / 40

Which protein complex is responsible for histone acetylation?

Histone kinase

Histone deacetylase (HDAC)

Histone acetyltransferase (HAT)

22 / 40

What is the term for the process by which cells "remember" their identity through cell division?

Epigenetic memory

Genetic inheritance

Cell differentiation

23 / 40

Which histone modification is commonly associated with enhancers?

H3K27me3

H3K27ac

H3K9me3

24 / 40

What is the effect of histone ubiquitination on gene expression?

Always represses genes

Always activates genes

It can signal either activation or repression

25 / 40

What is the primary function of histones in chromatin?

Gene transcription

RNA splicing

DNA packaging

26 / 40

What is the primary role of CpG islands in gene regulation?

DNA replication

RNA splicing

Regulating gene expression

27 / 40

What is the function of microRNAs (miRNAs) in gene regulation?

DNA replication

Post-transcriptional regulation

Protein degradation

28 / 40

What is the function of the enzyme DNMT1 in epigenetics?

DNA demethylation

De novo DNA methylation

Maintenance of DNA methylation

29 / 40

Which histone modification is involved in DNA damage response?

Methylation

Phosphorylation

Acetylation

30 / 40

Which histone modification is associated with gene silencing?

Phosphorylation

Acetylation

Methylation

31 / 40

Which type of chromatin is transcriptionally inactive and densely packed?

Polytene chromatin

Heterochromatin

Euchromatin

32 / 40

Which epigenetic mark is associated with actively transcribed genes?

H3K9me3

H3K4me3

H3K27me3

33 / 40

Which enzyme is responsible for adding methyl groups to DNA?

DNA methyltransferase

DNA ligase

DNA acetyltransferase

34 / 40

Which enzyme is responsible for removing acetyl groups from histones?

Histone methyltransferase

Histone acetyltransferase

Histone deacetylase (HDAC)

35 / 40

What is the role of non-coding RNAs in epigenetic regulation?

Regulating gene expression

Protein synthesis

DNA replication

36 / 40

What is the role of DNA methylation in genomic imprinting?

No effect

Activating imprinted genes

Silencing imprinted genes

37 / 40

What is the term for heritable changes in gene expression that do not involve changes in the DNA sequence?

Epigenetics

Genetics

Genomics

38 / 40

What is the role of histone deacetylases (HDACs) in gene expression?

Removing acetyl groups from histones

Adding methyl groups to histones

Adding acetyl groups to histones

39 / 40

Which histone modification is often found at active promoters?

H3K27me3

H3K4me3

H3K9me3

40 / 40

What is the term for the addition of ubiquitin to histones?

Histone methylation

Histone acetylation

Histone ubiquitination

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admin4 weeks ago

0 5 1 minute read