Immunodeficiency Disorders MCQs with Answers

adminApril 3, 2024

0 37 2 minutes read

Welcome to the Immunodeficiency Disorders MCQs with Answers. In this post, we have shared Immunodeficiency Disorders Online Test for different competitive exams. Find practice Immunodeficiency Disorders Practice Questions with answers in Biology Tests exams here. Each question offers a chance to enhance your knowledge regarding Immunodeficiency Disorders.

Immunodeficiency disorders are conditions that impair the immune system’s ability to respond effectively to infections and diseases. These disorders can be classified into primary (genetic) and secondary (acquired) types. Primary immunodeficiencies are often inherited and involve genetic mutations that affect immune cell function, leading to an increased susceptibility to infections. Examples include Severe Combined Immunodeficiency (SCID) and Common Variable Immunodeficiency (CVID).

Secondary immunodeficiencies, on the other hand, are acquired and can result from external factors such as infections, malnutrition, or the use of immunosuppressive medications. Human Immunodeficiency Virus (HIV) infection, which leads to Acquired Immunodeficiency Syndrome (AIDS), is a prominent example of a secondary immunodeficiency disorder.

Diagnosing immunodeficiency disorders involves a combination of clinical evaluation, immunological testing, and genetic analysis. Early diagnosis and intervention are crucial for managing these conditions and preventing severe complications. Treatments may include immunoglobulin replacement therapy, antibiotics to prevent infections, and in some cases, stem cell or bone marrow transplants.

Research in immunodeficiency disorders focuses on understanding the underlying genetic and environmental factors that contribute to these conditions. Advances in this field aim to improve diagnostic methods, develop targeted therapies, and enhance patient outcomes.

Immunodeficiency Disorders Online Quiz

By presenting 3 options to choose from, Immunodeficiency Disorders Quiz which cover a wide range of topics and levels of difficulty, making them adaptable to various learning objectives and preferences. You will have to read all the given answers of Immunodeficiency Disorders Questions and Answers and click over the correct answer.

Test Name: Immunodeficiency Disorders MCQ Quiz Practice
Type: Quiz Test
Total Questions: 40
Total Marks: 40
Time: 40 minutes

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Immunodeficiency Disorders

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1 / 40

Which disorder is characterized by an inability to clear certain fungal and bacterial infections?

Common Variable Immunodeficiency

DiGeorge Syndrome

Chronic Granulomatous Disease

2 / 40

Defects in the IL-2 receptor gamma chain can result in which immunodeficiency?

Selective IgA Deficiency

Chronic Granulomatous Disease

Severe Combined Immunodeficiency (SCID)

3 / 40

Hyper IgM Syndrome involves a defect in which gene?

TCR gene

CD40 ligand

IL-2 receptor

4 / 40

A patient with recurrent bacterial infections and low levels of all immunoglobulins might have?

Selective IgA Deficiency

Chronic Granulomatous Disease

Common Variable Immunodeficiency

5 / 40

In X-linked agammaglobulinemia, the BTK gene mutation affects the development of?

B cells

Natural killer cells

T cells

6 / 40

Common Variable Immunodeficiency (CVID) usually presents with?

Autoimmune disorders

Allergic reactions

Recurrent infections

7 / 40

Job's Syndrome is also known as?

Hyper IgM Syndrome

Hypogammaglobulinemia

Hyper IgE Syndrome

8 / 40

Ataxia-telangiectasia is associated with which kind of defect?

DNA repair

Protein folding

Enzyme production

9 / 40

What is a common treatment for many primary immunodeficiency disorders?

Antibiotics

Immunoglobulin replacement therapy

Antiviral drugs

10 / 40

Which primary immunodeficiency can present with eczema, thrombocytopenia, and recurrent infections?

Hyper IgM Syndrome

DiGeorge Syndrome

Wiskott-Aldrich Syndrome

11 / 40

Chronic Granulomatous Disease is diagnosed using which test?

Flow cytometry

ELISA

Nitroblue tetrazolium test

12 / 40

What is the treatment of choice for Bruton's Agammaglobulinemia?

Antifungal medication

Corticosteroids

Immunoglobulin replacement therapy

13 / 40

What is the genetic inheritance pattern of Wiskott-Aldrich Syndrome?

X-linked recessive

Autosomal recessive

Autosomal dominant

14 / 40

Selective IgA deficiency often results in?

Mucosal infections

Blood clotting disorders

Muscle weakness

15 / 40

Which of the following is a primary immunodeficiency disorder?

HIV/AIDS

Severe Combined Immunodeficiency (SCID)

Tuberculosis

16 / 40

What is the most common primary immunodeficiency?

Common Variable Immunodeficiency

DiGeorge Syndrome

Selective IgA deficiency

17 / 40

Hyper IgM Syndrome can result from mutations in which of the following?

Complement factor

CD40 ligand

IgA receptor

18 / 40

The primary cause of death in patients with Severe Combined Immunodeficiency (SCID) is?

Infections

Autoimmune diseases

Cancer

19 / 40

Which syndrome is associated with defective T-cell development and low calcium levels?

DiGeorge Syndrome

Hyper IgM Syndrome

Severe Combined Immunodeficiency (SCID)

20 / 40

Which primary immunodeficiency disorder involves a defect in the CD40 ligand gene?

Common Variable Immunodeficiency

Selective IgA Deficiency

Hyper IgM Syndrome

21 / 40

Hyper IgM syndrome is characterized by high levels of which immunoglobulin?

IgM

IgA

IgG

22 / 40

DiGeorge Syndrome is primarily caused by?

A deletion on chromosome 22

A mutation in the B cell receptor

An HIV infection

23 / 40

The "Boy in the Bubble" disease refers to?

Common Variable Immunodeficiency

X-linked agammaglobulinemia

Severe Combined Immunodeficiency (SCID)

24 / 40

Severe Combined Immunodeficiency (SCID) affects which cells?

Only T cells

Only B cells

Both B and T cells

25 / 40

Which enzyme deficiency leads to Severe Combined Immunodeficiency (SCID)?

Alpha-1 antitrypsin

Phosphofructokinase

Adenosine deaminase

26 / 40

Chronic mucocutaneous candidiasis is primarily due to a defect in which type of cell?

Phagocytes

T cells

B cells

27 / 40

The absence of mature B cells is indicative of which condition?

Hyper IgM Syndrome

Chronic Granulomatous Disease

X-linked agammaglobulinemia

28 / 40

The absence of the thymus is a hallmark of which syndrome?

Bruton’s Agammaglobulinemia

DiGeorge Syndrome

Common Variable Immunodeficiency

29 / 40

Ataxia-telangiectasia is associated with increased risk of which disease?

Cardiovascular disease

Cancer

Osteoporosis

30 / 40

Wiskott-Aldrich Syndrome is caused by mutations in which gene?

WAS gene

IL-2 receptor gene

BTK gene

31 / 40

Wiskott-Aldrich Syndrome includes symptoms like?

Thrombocytopenia, eczema, recurrent infections

Only eczema

Only recurrent infections

32 / 40

Which disorder is characterized by the inability to produce antibodies?

Lymphopenia

Neutropenia

Agammaglobulinemia

33 / 40

Which immunodeficiency is associated with defects in the phagocyte oxidase enzyme?

Wiskott-Aldrich Syndrome

Chronic Granulomatous Disease

DiGeorge Syndrome

34 / 40

A deficiency in which complement component can lead to recurrent Neisseria infections?

C5-C9

C1 esterase

35 / 40

Selective IgA deficiency mainly affects which immunoglobulin?

IgG

IgA

IgM

36 / 40

Which primary immunodeficiency involves a defect in neutrophil chemotaxis?

Leukocyte Adhesion Deficiency

Bruton’s Agammaglobulinemia

Common Variable Immunodeficiency

37 / 40

What is the main characteristic of X-linked agammaglobulinemia?

Overproduction of B cells

Lack of B cells

Deficiency of T cells

38 / 40

The diagnostic hallmark of Chronic Granulomatous Disease is?

Defective neutrophil function

Low immunoglobulin levels

Lack of thymus

39 / 40

Which primary immunodeficiency is often treated with bone marrow transplantation?

Hyper IgM Syndrome

Severe Combined Immunodeficiency (SCID)

Selective IgA Deficiency

40 / 40

Wiskott-Aldrich Syndrome affects which type of cells primarily?

Platelets and immune cells

Red blood cells

Endothelial cells

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adminApril 3, 2024

0 37 2 minutes read