Immunodeficiency Disorders MCQs with Answers

adminApril 3, 2024

0 30 2 minutes read

Welcome to the Immunodeficiency Disorders MCQs with Answers. In this post, we have shared Immunodeficiency Disorders Online Test for different competitive exams. Find practice Immunodeficiency Disorders Practice Questions with answers in Biology Tests exams here. Each question offers a chance to enhance your knowledge regarding Immunodeficiency Disorders.

Immunodeficiency disorders are conditions that impair the immune system’s ability to respond effectively to infections and diseases. These disorders can be classified into primary (genetic) and secondary (acquired) types. Primary immunodeficiencies are often inherited and involve genetic mutations that affect immune cell function, leading to an increased susceptibility to infections. Examples include Severe Combined Immunodeficiency (SCID) and Common Variable Immunodeficiency (CVID).

Secondary immunodeficiencies, on the other hand, are acquired and can result from external factors such as infections, malnutrition, or the use of immunosuppressive medications. Human Immunodeficiency Virus (HIV) infection, which leads to Acquired Immunodeficiency Syndrome (AIDS), is a prominent example of a secondary immunodeficiency disorder.

Diagnosing immunodeficiency disorders involves a combination of clinical evaluation, immunological testing, and genetic analysis. Early diagnosis and intervention are crucial for managing these conditions and preventing severe complications. Treatments may include immunoglobulin replacement therapy, antibiotics to prevent infections, and in some cases, stem cell or bone marrow transplants.

Research in immunodeficiency disorders focuses on understanding the underlying genetic and environmental factors that contribute to these conditions. Advances in this field aim to improve diagnostic methods, develop targeted therapies, and enhance patient outcomes.

Immunodeficiency Disorders Online Quiz

By presenting 3 options to choose from, Immunodeficiency Disorders Quiz which cover a wide range of topics and levels of difficulty, making them adaptable to various learning objectives and preferences. You will have to read all the given answers of Immunodeficiency Disorders Questions and Answers and click over the correct answer.

Test Name: Immunodeficiency Disorders MCQ Quiz Practice
Type: Quiz Test
Total Questions: 40
Total Marks: 40
Time: 40 minutes

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Immunodeficiency Disorders

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1 / 40

The diagnostic hallmark of Chronic Granulomatous Disease is?

Defective neutrophil function

Low immunoglobulin levels

Lack of thymus

2 / 40

Chronic mucocutaneous candidiasis is primarily due to a defect in which type of cell?

T cells

B cells

Phagocytes

3 / 40

The absence of mature B cells is indicative of which condition?

Hyper IgM Syndrome

Chronic Granulomatous Disease

X-linked agammaglobulinemia

4 / 40

Which disorder is characterized by an inability to clear certain fungal and bacterial infections?

DiGeorge Syndrome

Common Variable Immunodeficiency

Chronic Granulomatous Disease

5 / 40

What is the treatment of choice for Bruton's Agammaglobulinemia?

Antifungal medication

Immunoglobulin replacement therapy

Corticosteroids

6 / 40

Ataxia-telangiectasia is associated with increased risk of which disease?

Cancer

Osteoporosis

Cardiovascular disease

7 / 40

In X-linked agammaglobulinemia, the BTK gene mutation affects the development of?

Natural killer cells

T cells

B cells

8 / 40

Which of the following is a primary immunodeficiency disorder?

Severe Combined Immunodeficiency (SCID)

HIV/AIDS

Tuberculosis

9 / 40

Severe Combined Immunodeficiency (SCID) affects which cells?

Both B and T cells

Only T cells

Only B cells

10 / 40

Wiskott-Aldrich Syndrome is caused by mutations in which gene?

IL-2 receptor gene

WAS gene

BTK gene

11 / 40

Which enzyme deficiency leads to Severe Combined Immunodeficiency (SCID)?

Adenosine deaminase

Alpha-1 antitrypsin

Phosphofructokinase

12 / 40

What is the genetic inheritance pattern of Wiskott-Aldrich Syndrome?

X-linked recessive

Autosomal dominant

Autosomal recessive

13 / 40

What is the most common primary immunodeficiency?

Common Variable Immunodeficiency

DiGeorge Syndrome

Selective IgA deficiency

14 / 40

Which primary immunodeficiency can present with eczema, thrombocytopenia, and recurrent infections?

Hyper IgM Syndrome

Wiskott-Aldrich Syndrome

DiGeorge Syndrome

15 / 40

Which immunodeficiency is associated with defects in the phagocyte oxidase enzyme?

Wiskott-Aldrich Syndrome

Chronic Granulomatous Disease

DiGeorge Syndrome

16 / 40

A patient with recurrent bacterial infections and low levels of all immunoglobulins might have?

Common Variable Immunodeficiency

Selective IgA Deficiency

Chronic Granulomatous Disease

17 / 40

Which primary immunodeficiency is often treated with bone marrow transplantation?

Severe Combined Immunodeficiency (SCID)

Hyper IgM Syndrome

Selective IgA Deficiency

18 / 40

The absence of the thymus is a hallmark of which syndrome?

DiGeorge Syndrome

Common Variable Immunodeficiency

Bruton’s Agammaglobulinemia

19 / 40

Job's Syndrome is also known as?

Hyper IgM Syndrome

Hypogammaglobulinemia

Hyper IgE Syndrome

20 / 40

Which primary immunodeficiency disorder involves a defect in the CD40 ligand gene?

Selective IgA Deficiency

Common Variable Immunodeficiency

Hyper IgM Syndrome

21 / 40

Which syndrome is associated with defective T-cell development and low calcium levels?

Hyper IgM Syndrome

Severe Combined Immunodeficiency (SCID)

DiGeorge Syndrome

22 / 40

Hyper IgM syndrome is characterized by high levels of which immunoglobulin?

IgA

IgM

IgG

23 / 40

DiGeorge Syndrome is primarily caused by?

An HIV infection

A deletion on chromosome 22

A mutation in the B cell receptor

24 / 40

Defects in the IL-2 receptor gamma chain can result in which immunodeficiency?

Chronic Granulomatous Disease

Selective IgA Deficiency

Severe Combined Immunodeficiency (SCID)

25 / 40

Selective IgA deficiency mainly affects which immunoglobulin?

IgG

IgA

IgM

26 / 40

Selective IgA deficiency often results in?

Muscle weakness

Mucosal infections

Blood clotting disorders

27 / 40

Wiskott-Aldrich Syndrome affects which type of cells primarily?

Platelets and immune cells

Red blood cells

Endothelial cells

28 / 40

Which disorder is characterized by the inability to produce antibodies?

Agammaglobulinemia

Neutropenia

Lymphopenia

29 / 40

What is a common treatment for many primary immunodeficiency disorders?

Immunoglobulin replacement therapy

Antiviral drugs

Antibiotics

30 / 40

Hyper IgM Syndrome involves a defect in which gene?

IL-2 receptor

TCR gene

CD40 ligand

31 / 40

What is the main characteristic of X-linked agammaglobulinemia?

Lack of B cells

Deficiency of T cells

Overproduction of B cells

32 / 40

Chronic Granulomatous Disease is diagnosed using which test?

Nitroblue tetrazolium test

ELISA

Flow cytometry

33 / 40

Ataxia-telangiectasia is associated with which kind of defect?

DNA repair

Protein folding

Enzyme production

34 / 40

Common Variable Immunodeficiency (CVID) usually presents with?

Recurrent infections

Autoimmune disorders

Allergic reactions

35 / 40

Hyper IgM Syndrome can result from mutations in which of the following?

IgA receptor

Complement factor

CD40 ligand

36 / 40

The primary cause of death in patients with Severe Combined Immunodeficiency (SCID) is?

Cancer

Infections

Autoimmune diseases

37 / 40

Wiskott-Aldrich Syndrome includes symptoms like?

Thrombocytopenia, eczema, recurrent infections

Only recurrent infections

Only eczema

38 / 40

The "Boy in the Bubble" disease refers to?

X-linked agammaglobulinemia

Severe Combined Immunodeficiency (SCID)

Common Variable Immunodeficiency

39 / 40

A deficiency in which complement component can lead to recurrent Neisseria infections?

C5-C9

C1 esterase

40 / 40

Which primary immunodeficiency involves a defect in neutrophil chemotaxis?

Common Variable Immunodeficiency

Leukocyte Adhesion Deficiency

Bruton’s Agammaglobulinemia

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adminApril 3, 2024

0 30 2 minutes read