Immunodeficiency Disorders MCQs with Answers

adminApril 3, 2024

0 35 2 minutes read

Welcome to the Immunodeficiency Disorders MCQs with Answers. In this post, we have shared Immunodeficiency Disorders Online Test for different competitive exams. Find practice Immunodeficiency Disorders Practice Questions with answers in Biology Tests exams here. Each question offers a chance to enhance your knowledge regarding Immunodeficiency Disorders.

Immunodeficiency disorders are conditions that impair the immune system’s ability to respond effectively to infections and diseases. These disorders can be classified into primary (genetic) and secondary (acquired) types. Primary immunodeficiencies are often inherited and involve genetic mutations that affect immune cell function, leading to an increased susceptibility to infections. Examples include Severe Combined Immunodeficiency (SCID) and Common Variable Immunodeficiency (CVID).

Secondary immunodeficiencies, on the other hand, are acquired and can result from external factors such as infections, malnutrition, or the use of immunosuppressive medications. Human Immunodeficiency Virus (HIV) infection, which leads to Acquired Immunodeficiency Syndrome (AIDS), is a prominent example of a secondary immunodeficiency disorder.

Diagnosing immunodeficiency disorders involves a combination of clinical evaluation, immunological testing, and genetic analysis. Early diagnosis and intervention are crucial for managing these conditions and preventing severe complications. Treatments may include immunoglobulin replacement therapy, antibiotics to prevent infections, and in some cases, stem cell or bone marrow transplants.

Research in immunodeficiency disorders focuses on understanding the underlying genetic and environmental factors that contribute to these conditions. Advances in this field aim to improve diagnostic methods, develop targeted therapies, and enhance patient outcomes.

Immunodeficiency Disorders Online Quiz

By presenting 3 options to choose from, Immunodeficiency Disorders Quiz which cover a wide range of topics and levels of difficulty, making them adaptable to various learning objectives and preferences. You will have to read all the given answers of Immunodeficiency Disorders Questions and Answers and click over the correct answer.

Test Name: Immunodeficiency Disorders MCQ Quiz Practice
Type: Quiz Test
Total Questions: 40
Total Marks: 40
Time: 40 minutes

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Immunodeficiency Disorders

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1 / 40

What is the most common primary immunodeficiency?

DiGeorge Syndrome

Common Variable Immunodeficiency

Selective IgA deficiency

2 / 40

Which primary immunodeficiency is often treated with bone marrow transplantation?

Hyper IgM Syndrome

Selective IgA Deficiency

Severe Combined Immunodeficiency (SCID)

3 / 40

Which primary immunodeficiency can present with eczema, thrombocytopenia, and recurrent infections?

Wiskott-Aldrich Syndrome

DiGeorge Syndrome

Hyper IgM Syndrome

4 / 40

Which immunodeficiency is associated with defects in the phagocyte oxidase enzyme?

Chronic Granulomatous Disease

Wiskott-Aldrich Syndrome

DiGeorge Syndrome

5 / 40

The absence of the thymus is a hallmark of which syndrome?

Common Variable Immunodeficiency

Bruton’s Agammaglobulinemia

DiGeorge Syndrome

6 / 40

What is the main characteristic of X-linked agammaglobulinemia?

Lack of B cells

Overproduction of B cells

Deficiency of T cells

7 / 40

DiGeorge Syndrome is primarily caused by?

A mutation in the B cell receptor

A deletion on chromosome 22

An HIV infection

8 / 40

Hyper IgM syndrome is characterized by high levels of which immunoglobulin?

IgM

IgG

IgA

9 / 40

Common Variable Immunodeficiency (CVID) usually presents with?

Autoimmune disorders

Allergic reactions

Recurrent infections

10 / 40

Chronic Granulomatous Disease is diagnosed using which test?

Nitroblue tetrazolium test

Flow cytometry

ELISA

11 / 40

Which enzyme deficiency leads to Severe Combined Immunodeficiency (SCID)?

Adenosine deaminase

Alpha-1 antitrypsin

Phosphofructokinase

12 / 40

Severe Combined Immunodeficiency (SCID) affects which cells?

Only T cells

Both B and T cells

Only B cells

13 / 40

What is the treatment of choice for Bruton's Agammaglobulinemia?

Immunoglobulin replacement therapy

Antifungal medication

Corticosteroids

14 / 40

Which syndrome is associated with defective T-cell development and low calcium levels?

Severe Combined Immunodeficiency (SCID)

Hyper IgM Syndrome

DiGeorge Syndrome

15 / 40

A deficiency in which complement component can lead to recurrent Neisseria infections?

C1 esterase

C5-C9

16 / 40

Ataxia-telangiectasia is associated with increased risk of which disease?

Osteoporosis

Cardiovascular disease

Cancer

17 / 40

The primary cause of death in patients with Severe Combined Immunodeficiency (SCID) is?

Cancer

Autoimmune diseases

Infections

18 / 40

Ataxia-telangiectasia is associated with which kind of defect?

DNA repair

Protein folding

Enzyme production

19 / 40

The "Boy in the Bubble" disease refers to?

Common Variable Immunodeficiency

X-linked agammaglobulinemia

Severe Combined Immunodeficiency (SCID)

20 / 40

Which primary immunodeficiency disorder involves a defect in the CD40 ligand gene?

Common Variable Immunodeficiency

Hyper IgM Syndrome

Selective IgA Deficiency

21 / 40

A patient with recurrent bacterial infections and low levels of all immunoglobulins might have?

Selective IgA Deficiency

Chronic Granulomatous Disease

Common Variable Immunodeficiency

22 / 40

Job's Syndrome is also known as?

Hyper IgE Syndrome

Hypogammaglobulinemia

Hyper IgM Syndrome

23 / 40

Hyper IgM Syndrome can result from mutations in which of the following?

Complement factor

CD40 ligand

IgA receptor

24 / 40

The absence of mature B cells is indicative of which condition?

Hyper IgM Syndrome

X-linked agammaglobulinemia

Chronic Granulomatous Disease

25 / 40

In X-linked agammaglobulinemia, the BTK gene mutation affects the development of?

Natural killer cells

T cells

B cells

26 / 40

Which primary immunodeficiency involves a defect in neutrophil chemotaxis?

Common Variable Immunodeficiency

Bruton’s Agammaglobulinemia

Leukocyte Adhesion Deficiency

27 / 40

Which disorder is characterized by an inability to clear certain fungal and bacterial infections?

Chronic Granulomatous Disease

DiGeorge Syndrome

Common Variable Immunodeficiency

28 / 40

Wiskott-Aldrich Syndrome affects which type of cells primarily?

Platelets and immune cells

Red blood cells

Endothelial cells

29 / 40

Defects in the IL-2 receptor gamma chain can result in which immunodeficiency?

Chronic Granulomatous Disease

Selective IgA Deficiency

Severe Combined Immunodeficiency (SCID)

30 / 40

Selective IgA deficiency often results in?

Blood clotting disorders

Mucosal infections

Muscle weakness

31 / 40

Chronic mucocutaneous candidiasis is primarily due to a defect in which type of cell?

Phagocytes

B cells

T cells

32 / 40

Wiskott-Aldrich Syndrome includes symptoms like?

Only eczema

Thrombocytopenia, eczema, recurrent infections

Only recurrent infections

33 / 40

The diagnostic hallmark of Chronic Granulomatous Disease is?

Lack of thymus

Defective neutrophil function

Low immunoglobulin levels

34 / 40

Which disorder is characterized by the inability to produce antibodies?

Lymphopenia

Neutropenia

Agammaglobulinemia

35 / 40

Wiskott-Aldrich Syndrome is caused by mutations in which gene?

BTK gene

WAS gene

IL-2 receptor gene

36 / 40

Which of the following is a primary immunodeficiency disorder?

Tuberculosis

Severe Combined Immunodeficiency (SCID)

HIV/AIDS

37 / 40

Selective IgA deficiency mainly affects which immunoglobulin?

IgM

IgA

IgG

38 / 40

What is the genetic inheritance pattern of Wiskott-Aldrich Syndrome?

Autosomal dominant

X-linked recessive

Autosomal recessive

39 / 40

What is a common treatment for many primary immunodeficiency disorders?

Antibiotics

Immunoglobulin replacement therapy

Antiviral drugs

40 / 40

Hyper IgM Syndrome involves a defect in which gene?

CD40 ligand

TCR gene

IL-2 receptor

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adminApril 3, 2024

0 35 2 minutes read